ncRNA name | rno-miR-29a |
ncRNA Category | miRNA |
Disease name | age-related cataract |
Species | Rattus norvegicus |
Tissues/Cell_line | lens; lens epithelial cells (LECs) |
Methods | microarray, qRT-PCR, transfection, protein blot, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | 44 miRNAs were down-regulated in 4W and 14W lenses in comparison with prenatal ED16 lenses. When the luciferase gene carried 3′ UTR region of TM1α's transcript, the luciferase activity was not significantly inhibited by overexpressing miR29a. |
PubMed ID | 23844765 |
Year | 2013 |
Title | Dynamic and differential regulation in the microRNA expression in the developing and mature cataractous rat lens. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.